냉동 건조 탈회 동종골 이식후 골막이 골 형성 과정에 미치는 영향에 관한 실험적 연구
Experimental study of effects of the periosteum on bone formation process after freezed dried dermineralized allogeneic bone grafts
권혁도, 최기룡, 김성숙, 이몽룡,
소속 상세정보
권혁도 ( ) - 원광대학교
최기룡 ( ) - 원광대학교
김성숙 ( ) - 원광대학교
이몽룡 ( ) - 원광대학교
KMID : 0360119950170040337
Abstract
Periosteum in general is described as a specialized fibrous membrane of mesenchymal origin consisting of two basic layers : outer fibrous layer consists of irregularly arranged dense connective-tissue with fibroblasts, and inner osteogenic or
cambial
layer is composed of more loosely arranged fibers, greater vascularity and flatted spindle-shaped pre-osteoblasts.
This periosteum may serve in controlling bone growth, especially mandibular growth has been emphasized. But, the periosteum enwrapping the facial skeleton have been studied for many years leaving a controversy in opinion regarding the function of
these
structures.
We evaluated the bone formation activity of te periosteum in allogeneic bone grafts which bones are made of freeze-dried preparation preoperatively. We made the calvarial bone defects, 5×7mm sized, amd grafted with allogeneic bone in rats, which
a
half
of specimens has dissected the overlying periosteum and a rest intacted. After bone grafting, we evaluated the capacity ofbone formation of periosteum, 1, 2, 4, 6, 8 weeks postoperatively.
There are subtle aifferences of bone formation during early healing period after demineralized allogeneic bone grafting between control groups with periosteum and experimental groups without periosteum.
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